![]() ![]() As a result, more attention should be paid to the vulnerable group to reduce the risk of NAFLD and its associated complications and mortality. Approximately 20%–30% of individuals with NAFLD develop non-alcoholic steatohepatitis (NASH), which progresses into cirrhosis in 10%–20% of cases. Moreover, NAFLD is currently the most important emerging cause of hepatocellular carcinoma (HCC) in developed countries. ![]() NAFLD poses a significant threat to people’s health and imposes a great burden on the social economy. With changes in dietary and lifestyle habits, non-alcoholic fatty liver disease (NAFLD) has become the most prevalent liver disease in both developed and developing countries, with a current global incidence of approximately 25%. In this cross-sectional study, daytime napping duration of ≥ 60 min was positively associated with the risk of non-alcoholic fatty liver disease in an occupational population of Guangdong Province after multivariable adjustment. The association was moderately enhanced with additional adjustments for night sleep duration and socioeconomic or other factors (odds ratio 2.253 95% confidence interval 1.061–4.786, P = 0.035). ResultsĬompared with non-nappers, long daytime nappers (≥ 60 min) were associated with a higher risk of non-alcoholic fatty liver disease in the crude model (odds ratio 2.138 95% confidence interval 1.88–2.61, P < 0.05) and in the multivariable adjustment model (odds ratio 2.211 95% confidence interval 1.042–4.690, P < 0.05) after adjusting for demographic, educational, and metabolic risk factors. The outcome was the association between daytime sleep duration and the risk of non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease was diagnosed using abdominal ultrasonography. A total of 3363 participants aged 20–79 years were recruited and admitted from January 20, 2018, to October 16, 2020. This cross-sectional study analyzed data from the Health Management Center of Nanfang Hospital, Guangdong Province. This study aimed to investigate the association of daytime napping duration with the risk of non-alcoholic fatty liver disease in a Chinese population. However, few studies have investigated the association between daytime napping duration and the risk of non-alcoholic fatty liver disease. A lack of sleep or disorder in sleep–wake cycles has been associated with metabolic impairments. ![]()
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